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Thus, CRISPRCas9 therapy targeting p53 should be used with caution

These mechanisms may provide an important direction for an in-depth study of the pathogenesis of vitiligo

This challenge is compounded by the declining trend in the development of novel antibiotics, with a documented 75 percent reduction in new approvals by the United States Food and Drug Administration between 1983 and 2007 [17]

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In Arabidopsis , two genes encode GR, called GR1 encoding a cytosolic and peroxisomal protein, and GR2, found in chloroplast and mitochondria, which is lethal when it is inactivated at an early stage of embryo formation (Meyer et al., 2012)