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Virchows Arch B Cell Pathol Incl Mol Pathol
Cellular Energy and Aging Aging is often described at a cellular level as the accumulation of oxidative damage over time
No MTD was determined
2b) and therefore we used cell size normalization in the quantification of lysosome positioning (see Methods section)
Free Radic Res 2008
Curcumin exerts context-specific autophagy regulation through dual mechanisms: At moderate concentrations (2025 M), it promotes cytoprotective autophagy via inhibition of the mechanistic target of rapamycin (mTOR)-AKT axis (Zhao et al., 2016), evidenced by decreased p-AKT, p-mTOR, and p-P70S6K expression, coupled with increased microtubule-associated protein 1A/1B-light chain 3- II/microtubule-associated protein 1A/1B-light chain 3-I (LC3-II/LC3-I) conversion
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