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We connected the whole body model of acetaminophen metabolism to our previously constructed model of glutathione metabolism[9] so that we could study the depletion of GSH after APAP doses of various sizes (Figure6)

Profiling at mRNA, protein, and metabolite levels reveals alterations in renal amino acid handling and glutathione metabolism in kidney tissue of pept2 / mice

Baldwin, A

8, 2024 from Medline Plus

15 In the presence of ROS, rGSH is converted to GSSG by glutathione peroxidase (GPx) (Figure 3)