glutathione and antibiotics does lower creatinine levels Autism & Undermethylation; Mitochondria, Oxidative Stress, Folate Nutritional Intervention Musculoskeletal Health – Effect of glutathione on antibiotic

Treatment of chronic postinfectious fatigue: Randomized double-blind study of two doses of sulbutiamine (400-600 mg/day) versus placebo

So if B12 has a role, wed expect diffuse shedding or telogen effluvium-type presentation

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The larger vial size reflects typical dosing in preclinical protocols in which TB-500 is administered systemically and requires higher absolute amounts.

An intradermal test dose is recommended before administration in patients suspected of being sensitive to the drug

This could be daily, weekly, monthly, or at other intervals appropriate for your physiology