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Presented at the American Heart Associations 2023 Scientific Sessions (1113 November, Philadelphia, USA), the results of the SELECT trial showed that overweight or obese people without diabetes taking semaglutide for more than three years had a 20% lower risk of heart attack, stroke or death due to cardiovascular disease and lost an average of 9.4% of their body weight
However, GLP-1 receptors exist throughout the cardiovascular system, including in heart tissue and blood vessel walls
20% higher D30 engagement from new features launched September 22, 2025 is based on a pre-post analysis from August 22 to October 24, 2025 of D30 engagement in key in-app behaviours (completing any Home Screen Task, tapping the Bank button to bank rewards for steps, viewing the Health Report, logging medication, or reading an article)
During periods of caloric restriction and weight loss, supplemental glycine supports muscle protein synthesis and may help preserve lean mass
Accepted 2026-3-13
Ramos-Casals, M
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