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In vitro experiments have shown that GSH deficiency induced by either the siRNA approach or pharmacological inhibition of the GCL rate-limiting enzyme decreases GSH biosynthesis and escalates oxidative stress in cultured hepatocytes
J., Zheng, J
Typically, larger unilamellar vesicles provide greater bilayer surface area, facilitating enhanced drug incorporation
Moreover, it has the ability to protect DNA and to reduce chromosomal fragmentation 104
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