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For now, and in the context of GLP therapy, it will be important to first better understand the insulin release and response kinetics in normal weight, nondiabetic patients before recommending these meds for a broader population.

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The most significant marker, considered a gold standard, was F2-isoprostane and this was significantly more reduced by oral Acetylglutathione than with the IV glutathione.[11],[12] Oral S-Acetyl Glutathione, dosed 200mg daily for 7 days, AM IV 1400mg, single dose Serum and urine tested after 1 week of administration N=6, (4 female, 2 male, average age 45) Markers chosen are measures of Antioxidants F2-Isoprostane is the Gold Standard of oxidative stress markers Conclusion: Oral S-A GSH compares favourably to a one-time, equivalent dose of IV administered Glutathione GSH : Blood levels are lower in the A-GSH group as compared to the IV group because the A-GSH is being taken up by the cell.[13] This is substantiated by the following markers: F2-Iso : (F2- isoprostane ) measurement of redox status and oxidative stress

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