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Initially, GLP-1 agonists were used mainly to lower blood sugar levels and hemoglobin A1c in diabetic patients

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A key double-blind, placebo-controlled phase II study conducted over 72 weeks recruited 320 individuals with histologically confirmed NASH and liver fibrosis classified as stage F1 to F3

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In addition, SSTR-2 mRNA expression in the pituitary gland was decreased in the treatment group, compared to the control group (Fig

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