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The hyaluronic acid receptor CD44 is significantly overexpressed in pancreatic, lung, ovarian, and breast cancers (Naor et al., 2002)
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Gastrointestinal complications (gastroparesis): GLP-1 medications slow digestion by delaying stomach emptying
But the mere presence of the enzyme does not guarantee its high activity
TeSlaa, T., Ralser, M., Fan, J
To overcome drug resistance and enhance its cytotoxicity, two derivatives of DOX were synthesized incorporating a sulfonamide moiety: 4-mononitrobenzenesulfonyl DOX (MNS-DOX) and 2,4-dinitrobenzenesulfonyl DOX (DNS-DOX) 94
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