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Introduction to Cagrilintide 10mg Cagrilintide , biochemically classified as a long-acting lipidated or acylated analogue of the endogenous pancreatic hormone amylin, is a synthetic peptide engineered to serve as a high-resolution molecular probe in endocrinology, metabolic biochemistry, and obesity trials

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Phase 2 trial (NEJM, 2023) The landmark Phase 2 trial, published in the New England Journal of Medicine, randomized 338 adults with obesity to receive weekly subcutaneous retatrutide at doses of 1 mg, 4 mg, 8 mg, or 12 mg, or placebo, for 48 weeks