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Pentadecapeptide BPC 157, in clinical trials as a therapy for inflammatory bowel disease, counteracts NSAID-induced intestinal damage
After gel formation, 1 10 5 HUVECs pretreated with or without BPC 157 for 24 h were seeded into each well with 0.5 ml of M199 supplemented with 16% fetal bovine serum and 20% EGM-2
Blood was flushed out with 150 mL of saline with 100 U/L heparin at 30 mL/min, followed by perfusion with 3% formaldehyde and 150 mL of 1% glutaraldehyde solution
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While research on BPC-157, particularly in United States human trials, is ongoing and has shown promising results, it is primarily available for research purposes
