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The best rank structure of each complex was further calculated TM-score, RMSD, pLDDT, and interface pAE

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At the proteolytic level, GLP-1 RAs may reduce muscle protease activity and modulate inflammatory pathways, thereby attenuating protein breakdown and contributing to muscle mass preservation [39, 84]

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But unlike in general weight management, athletes have different energy needsand the downsides of semaglutide are particularly relevant in this population