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It is important to distinguish between dark urine caused by concentration (which appears deep yellow to amber and clears with increased fluid intake) and abnormal pigmentation suggesting pathology (such as tea-coloured urine indicating bilirubin, or red-brown urine suggesting blood or myoglobin)
The first is during the initial titration phase, when the body is adjusting to a new medication that fundamentally changes how the digestive system operates
References Danaei G, et al
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