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There are some dramatic left-tail-risk scenariosfor example, if all people with above-average body mass index take GLP-1 medications and stick to the prescribed regimen for a prolonged period, this could drive a decline in food consumption of more than 10%

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Image Credit: Monkey Business Images / Shutterstock In a recent study published in the journal Nature Medicine , researchers used "target trial emulation" to analyze a decade of clinical data on the long-term outcomes associated with glucagon-like peptide-1 receptor agonists (GLP-1RAs) in type 1 diabetes (T1D)

The 28-day window comes from Pfizer/Hospira prescribing information for bacteriostatic water for injection

However, they can also lead to nutrient depletion and digestive discomfort, including nausea, constipation, and digestive irregularity