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A randomized, placebo-controlled study in 52 subjects (mean age, 30 years) with relapsing-remitting multiple sclerosis found an increase in total antioxidant capacity in blood with lipoic acid supplementation (1,200 mg/day for 12 weeks) yet not in the activity of specific antioxidant enzymes (superoxide dismutase and glutathione peroxidase) (97)

In the penumbra and reperfused peri-infarct region, however, MSC-derived paracrine and vasoactive signals may improve microvascular oxygen delivery and reduce hypoxia-driven glycolysis [10, 14]

A 1993 study evaluated the effect of 500 mg to 2,000 mg of vitamin C on red blood cell (RBC) glutathione levels

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Dietary triglyceride and cholesterol, as well as triglyceride and cholesterol synthesized by the liver, are solubilized in lipid-protein complexes

joint CCP4+ ESF-EAMCB Newsletter on Protein Crystallography 26 (1992)