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Standard Dose 0.5 mg (500 mcg) Standard loading dose after initial tolerance

Briefly, a density gradient fractionation system was used to generate a polysome profile, distinguishing fractions that correspond to 40S (fractions 4 to 6), 60S (fractions 6 to 8), 80S monosomes (fractions 8 to 10), low-molecular-weight polysomes (fractions 10 to 13, LP), and high-molecular-weight polysomes (fractions 13 to 15, HP)

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Proc Natl Acad Sci USA 89: 76747677