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It outperformed placebo, GLP-1 receptor agonists, and insulin

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Animal models of obesity have come into play during the preclinical efficacy studies for GLP-1 RA drug development, and high-fat diets are commonly used to induce obesity in animals for studies in certain therapeutic areas, including GLP-1 RA development

Endocrinology Research: This combination is studied for its effects on the incretin-amylin hormonal axis and pancreatic beta-cell function

10.3390/pharmaceutics11020078 84 WanW.QinQ.XieL.ZhangH.WuF.StevensR

It works by mimicking the action of the naturally occurring hormone GLP-1