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Additionally, GLP-1 receptors in the hypothalamus interact with key appetite-regulating neuropeptides, including pro-opiomelanocortin (POMC) and neuropeptide Y (NPY)

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Luo W, Zhao M, Dwidar M, Gao Y, Xiang L, Wu X, et al

Clinical trials have shown different average weight loss outcomes, though direct comparison across trials is unreliable

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