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GLP-1 medications have also been associated with: Worsening of diabetic retinopathy Exacerbation of age-related macular degeneration Optic nerve complications, including NAION These risks dont mean you should stop taking your medication, but they do show why its important to have an eye exam before starting and regular follow-up exams while on treatment

If these effects impact your daily life, try adopting lifestyle changes to help you return to your normal routines

Wegovy is the brand-name version specifically FDA-approved and dosed for chronic weight management

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Within activated macrophages there are distinct changes in TCA cycle activity that lead to the accumulation of TCA cycle intermediates, particularly fumarate and itaconate

In the pancreas, activation stimulates glucose-dependent insulin secretion, meaning insulin is released only when blood glucose levels are elevated, which reduces the risk of hypoglycemia compared to some other diabetes medications