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It's important to note that some diabetes medications, particularly SGLT2 inhibitors (such as dapagliflozin, empagliflozin) which are sometimes co-prescribed with tirzepatide, do directly increase urination as part of their mechanism of action

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Both peptides bind to the Growth Hormone Secretagogue Receptor type 1a (GHS-R1a) on pituitary somatotropes, triggering pulsatile GH release

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These data indicate that GLP-1 protects islet cells against cholesterol-induced toxicity through the activation of AMPK, and LXR might be involved

CagriSema has also shown superiority over Ozempic in the REIMAGINE study