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Some clinical scenarios support combination therapy using both peptides sequentially or concurrently

Orlistat (Xenical/Alli), a lipase inhibitor available on the NHS, typically produces mean weight loss of around 35% compared with placebo over 12 months, making it a modest option for many patients

State-licensed pharmacies must stop making most compounded semaglutide (copies of Novo Nordisks Wegovy and Ozempic) by April 22, and larger outsourcing pharmacies by May 22, pending any court rulings

Evidence and Guidance Glucagon-like peptide-1 (GLP-1) receptor agonists, including semaglutide and liraglutide, are increasingly prescribed for type 2 diabetes and weight management in the UK

S., Son, H