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Once the AMPK signalling pathway is activated, it regulates key enzymes in several metabolic pathways, including lipid and glucose metabolism, mitochondrial dynamics, autophagy, and protein synthesis through phosphorylation, thereby helping to restore mitochondrial energy homeostasis [96, 97], which, when disrupted, damages mitochondria
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However, pregnant women should always consult with their healthcare provider before starting any supplementation program
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It should be noted that recent studies have shown convergence between these two pathways such that AMPK activation is an upstream event of the NRF2-mediated antioxidant response 53
2002, pp
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