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Although both ENDO3 and ENDO12 contain an azo functional group, their inhibitory effect is specific, as they effectively inhibited eTLR activation in the SEAP colorimetric assay, in selective fluorescence-based TR-FRET assays and in immunological assays using primary cells with cytokine production as the readout

The study was also supported by the NIHR Sheffield Biomedical Research Centre (NIHR203321) and the NIHR Sheffield Clinical Research Facility

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There are many different views about the long-term use of these medications, but we do not ask the patient with hypertension or diabetes to discontinue their medications when they become controlled, she explains

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4 Its main role is to neutralize free radicalsunstable molecules that can damage cellsthus protecting the body from oxidative stress and inflammation