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Transcriptional activation of G6PD in response to oxidative stress is carried out by the transcription factor, NRF2 (nuclear factor erythroid 2related factor 2)
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Following our previously reported protocols with the NanoBiT tethering strategy 11 , the structures of retatrutideGLP-1RG s , retatrutideGIPRG s and retatrutideGCGRG s were determined using the single-particle cryo-EM with overall resolutions of 2.68 , 3.26 and 2.84 , respectively (Fig
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