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GLP-1-based treatments may be recommended for individuals who: Not all patients are candidates for GLP-1/GIP-based weight loss treatments

Visceral fat is metabolically active and associated with increased health risks, which is why addressing it matters beyond appearance

They are part of a larger group of incretin mimetics

Elevated leptin in obesity often reflects leptin resistance, where impaired hypothalamic signaling and reduced leptin transport across the bloodbrain barrier limit its appetite-suppressing effects [68, 69]

Disturbingly, tan lines are trending on TikTok as a sought after summer accessory and the hashtag #sunburnttanlines has millions of views

It is important to remember that the majority of the current evidence is from animal studies or preliminary clinical trials and that to date, there is little information available on the side effects