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When PUFAs are excessively attacked by ROS, lipid hydroperoxides (LOOH) are generated (18)
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No published trials have reported alterations in methylation pathway markers (like homocysteine or methylmalonic acid), but this has not been systematically studied in long-term human use
Authors showed that Cxcr4 downregulation was responsible for the ectopic migration, as restoration of Cxcr4 by a GFP-retrovirus in the dentate gyrus of 4-week-old mice, led to correct localization of new neurons (GFP/NeuN + ) and decreased the seizures induced by Kainic acid
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