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Myelin is damaged with normal ageing and in several neurodegenerative diseases, such as multiple sclerosis and Alzheimer disease

doi:10.1002/art.11014 33

People who are pregnant or breastfeeding (many medications lack sufficient safety data)

11 Four randomised trials comparing myo-inositol with metformin found no significant differences in clinical pregnancy rates between the two

It is also worth noting the regulatory context honestly: many peptides used in performance protocols are not FDA-approved for body composition, and Tesamorelin's approval is specific to HIV-associated lipodystrophy