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Quinolones: Nitrofurantoin antagonized in vitro antibacterial action of quinolones (nalidixic acid, norfloxacin, oxolinic acid) losing anti-infective effectiveness

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To address this issue, individually housed mice were provided with a restricted amount of pellets (1520 g), and the remaining food was measured every 24 h

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Then the pellets were stained for 20 min in 100 l assay buffer containing 5 g ml 1 propidium iodide (Sigma-Aldrich, P4170) and 3 l Annexin VFITC (BioLegend, 0640906)