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Certificates of Analysis (COAs) are available on request COAs correspond directly to the supplied products Independent analytical testing does not constitute regulatory approval or authorisation for human or veterinary use
Groups at higher risk of deficiency include older adults (due to reduced stomach acid production), people following vegan or strict vegetarian diets (as B12 is naturally found almost exclusively in animal products), individuals with pernicious anaemia or other malabsorption conditions, those taking certain medications such as metformin or proton pump inhibitors long-term, and people with significant nitrous oxide exposure (including recreational use), which can inactivate B12 in the body
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It is crucial to note that there is no official link definitively proving that elevated B12 causes these conditions , but observational studies have identified correlations warranting clinical awareness
Cell-culture research has shown that reducing NNMT was associated with less lipid accumulation in fat cells, while increasing NNMT was associated with more suggesting NNMT contributes to adipocyte function rather than simply marking metabolic dysfunction