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GLP-1RAs are widely used for the treatment of type 2 diabetes mellitus (T2DM)
Total protein amounts were detected in parallel by the BCA assay (Pierce BCA Protein assay Kit) for normalization of glutathione levels
This kind of preclinical model is invaluable
For the assessment of the changes from baseline following GLP-1-based therapies in % FMD and IMT, mean differences with 95% confidence intervals (CI) were calculated between baseline samples and end-of-treatment samples for each study and then an overall effect size was generated
Consent for Publication This manuscript has not been published or presented elsewhere in part or entirety and is not under consideration by another journal
The blend is well tolerated, with gastrointestinal effects being the most frequent adverse events and no evidence of clinically significant safety concerns or neutralizing antibody responses to cagrilintide during short-term exposure 1-3
