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It catalyzes the formation of acetaldehyde by transferring hydrogen from the OH group to the nicotinamide cofactor of nicotinamide adenine dinucleotide (NAD+) to convert it into the reduced form of the molecule NADH

According to the specific oxidation position, the 12/15-LOX is in charge of catalyzing AA to 12-/15- hydroperoxyeicosatetraenoic acid (12-/15-HpETE) (Ackermann et al., 2017)

"The appeal is real, because it skips digestion and acts fast, which is exactly why it has earned its place in the wellness world," she says

The long-term benefits and side effects are unknown within the human body

All timelines beyond 12 weeks in this article are extrapolations based on the mechanism of action and user reports, not clinical evidence

These results show that although the expected therapeutic effect has not been achieved, AVV-based therapy has acceptable safety