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GLP-1 receptor agonists in heart failure GLP-1 receptor agonists have demonstrated favorable cardiovascular effects in patients with T2DM and obesity as meta-analyses suggest a reduction in hospitalization for incident or new-onset HF of approximately 18%, alongside reductions in major adverse cardiovascular events [6, 14, 15]
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457 The basket trial of KY100001K uses IDH mutation as the core enrollment criterion, overcoming tumor tissue-of-origin constraints to efficiently evaluate its efficacy and safety across multiple cancer types, thereby accelerating the precise development of rare molecular subtypes and providing a rationale for pancancer applications
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