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OASIS 4 was a 64-week efficacy and safety phase 3b trial of once-daily oral semaglutide 25 mg versus placebo in 307 adults with obesity or overweight with one or more comorbidities.
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The trial found that almost 63% of those taking semaglutide had a reduction in liver inflammation , compared to 34% in the placebo group
If administered growth hormone, they can achieve normal height
Clinical trials suggest that brand-name tirzepatide can produce slightly greater weight loss on average compared to semaglutide
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