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Additionally, safflower yellow pigments reduced plasma levels of endothelin, matrix metalloproteinase-9 (MMP-9), high-sensitivity c-reactive protein (hs-CRP), and platelet aggregation rates, thereby mitigating inflammatory responses and myocardial ischemic injury in patients with coronary heart disease

In our study, by performing metabolite pool and isotopomer labeling analyses, we found that ACTL6A increased GSH de novo synthesis mainly by regulating the synthesis of -GC, the rate-limiting step catalyzed by GCLC

W., Zhang, J., & Wang, R

TNF- evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor