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308 Rather than harboring stable resistance mutations, DTP cells adopt a slow-cycling or quasiquiescent phenotype driven by extensive epigenetic remodeling, transcriptional plasticity and metabolic reprogramming, which collectively constitute core maintenance programs that stabilize the DTP state under therapeutic pressure

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Scientific Note: Although there is much anecdotal evidence supporting the effectiveness of lipotropic injections alone, the scientific community has not fully validated the clinical effectiveness

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