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In most cases, timing does not affect safety, as confirmed interactions are uncommon

Presented for research literature review only Freda PU (2009)

NICE guidance recommends assessing response at 6 months, with continuation only if you've achieved an HbA1c reduction of at least 11 mmol/mol (1.0%) and weight loss of at least 3% (where weight loss is part of your treatment goals)

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