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For extended periods, storage at 20 C is recommended
Gastroenterology 2006
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Off label use for energy or performance is generally out of pocket
"Two concentrations of topical tretinoin (retinoic acid) cause similar improvement of photoaging but different degrees of irritation: a double-blind, vehicle-controlled comparison of 0.1% and 0.025% tretinoin creams." Archives of dermatology 131.9 (1995): 1037-1044
Bacteriostatic-water preparations are especially awkward because the solution chemistry changes during freezing and thawing
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