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Melatonin prevents Nrf2 degradation and augments its nuclear accumulation by inhibiting proteasomal [204]

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GLP-1 receptor agonists work by mimicking the action of naturally occurring GLP-1, a hormone that stimulates insulin secretion in response to food intake, suppresses glucagon release, slows gastric emptying, and promotes satiety

D2 receptor activation inhibits norepinephrine release, also contributing to vasodilation

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