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A 2025 real-world safety comparison found the two drugs had distinct safety profiles, rather than one being safer overall

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This broad expression spectrum increases the risk of off-target accumulation, which may exacerbate GLP-1RA-associated side effects including nausea, delayed gastric emptying, tachycardia, and arrhythmias

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Methods GHSR expression and purification All primers used in this study are listed in Supplementary Table 2