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Moving forward, the most realistic near-term translational path lies in combining relatively simple, biocompatible bone-targeted nanocarriers (such as alendronate-functionalized liposomal or polymeric systems) to specifically co-deliver immunogenic cell death (ICD)-inducing standard chemotherapeutics alongside established immune checkpoint inhibitors (e.g., anti-PD-1/PD-L1) or myeloid cell modulators
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Smith MG, Des Etages SG, Snyder M
They have patterns of damage across multiple joints and soft tissue areas that a single injection site cannot address
Potential AMD targets and pulmonary fibrosis (PF)-related genes were obtained from toxicity databases and transcriptomic data (GEO datasets), respectively, and intersected to identify candidate AIPF targets
Apresenta molcula ativa com tamanho suficiente para penetrar na hipoderme (local onde a celulite formada)
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