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The Journal of Clinical Investigation
It is found in a variety of foods such as fish, shellfish, meats, and dairy products
Studies on MOTS-c highlight its role in mitochondrial signaling, insulin sensitivity, and metabolic regulation
02 Mechanism of Action NNMT methylates nicotinamide to produce 1-methylnicotinamide (1-MNA), consuming SAMe and depleting cellular NAD+ pools
Deficiency is also prevalent in seniors because the capacity to absorb vitamin B12 can diminish with age
Memory loss and a loss of neurons is related to below normal B12 levels
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