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Site rotation (abdomen, thighs, upper arms) is the commonly reported approach to reduce this reaction
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This activity helps reduce the burden on the liver, kidneys, and other organs that are responsible for filtering waste
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Some precursor is absorbed into the bloodstream in the small intestine before reaching the gut (the RDI of choline is 450550 mg per day, [15] which is absorbed this way), however there is a limit to the transport capacity of the intestine, and not all precursor is exposed to the process
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