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Identifying the Strong Response Endotype For the study, researchers conducted a secondary analysis of data from a previous clinical trial of tirzepatide in patients with OSA and obesity
Oxidative stress is involved in endothelial damage resulting from endothelial malfunction, which increases endothelial permeability and inflammatory cell infiltration in the arterial wall [69]
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One study, which also evaluated cognitive function in patients with high MMA concentrations, found no significant effects on the MDD inventory score, but only 30 of the 140 subjects had depression at baseline, which may have diluted any benefits
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