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15 Phase II trials targeting MASH have shown that treatment with SEMA 0.4 mg daily for 72 weeks resulted in more patients with liver fibrosis stage F2/F3 achieving improvement in MASH without progression of liver fibrosis (odds ratio = 6.87, 95% CI = 2.6017.63) compared to placebo

and decrease joint and muscle pain

While most data suggest these medications are safe for patients with mental health conditions, your provider needs to be aware of your mental health history to provide appropriate monitoring and support

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The Src-Caveolin-1-eNOS pathway produces nitric oxide for vasodilation and improved blood flow

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