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In some countries, this has led to severe drug shortages and challenges for the diabetic population

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IL-11R-targeted polymersomes encapsulating doxorubicin (IL11-PDox) demonstrated significantly augmented internalization and apoptotic activity in IL-11R-overexpressing osteosarcoma cells, leading to striking repression of tumor growth and lung metastasis in orthotopic and relapsed models (60)

Thyroiditis (inflammation of the thyroid), which may occur in pregnancy or in the context of some autoimmune conditions, is another uncommon cause of hyperthyroidism

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