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Retatrutide is a synthetic peptide based on a glucose-dependent insulinotropic polypeptide (GIP) backbone, but uniquely, it functions as a triple agonist
- As of 2026, compounded GLP-1s remain in a shifting regulatory state
AstraZenecas extended-release formulation of omeprazole (Nexium) generated years of additional exclusivity after the base compound patent on omeprazole expired
A recent study (7) found that people taking GLP-1 medications frequently fall short of recommended daily intakes for several essential nutrients, including fibre, calcium, magnesium, potassium, iron, choline, and vitamins A, C, D, and E
Wegovy remains an excellent option for patients with more modest goals, established response to GLP-1 therapy, or specific cost and access considerations
Drug Resist Update
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