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Am J Physiol Gastrointestinal liver Physiol (2008) 294(4):G87784

Anderson, A

Some patients may require an even higher dose of 2 mg weekly for optimal effect, particularly for weight management indications, though this should be approached cautiously with careful monitoring for adverse effects

Seek immediate medical attention if you experience: bloody or black stools, severe abdominal pain, signs of significant dehydration (no urine output for 8+ hours, rapid heart rate, confusion), fever above 101F (38.3C), or diarrhea lasting more than 7 consecutive days without improvement

4th, Khalil, S