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Cellular response to oxidative stress: signaling for suicide and survival

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Forty-two thiophene benzodiazepine derivatives (compounds 445 ) were first designed and synthesized and seven compounds (compound 21 and compounds 3136 ) were selected by analyzing their tectonic relationships for better ferroptosis inhibition activity (Jiang et al., 2023)

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Alterations in NAD metabolism are critically linked to neurodegenerative disorders, as the accumulation of nicotinamide mononucleotide exerts pro-degenerative effects on axons, whereas enhancing its metabolism may rescue axons from degeneration (13, 53)

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