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"They lose weight, which is a positive thing," says Warren Yacawych of the University of Michigan, "but they experience such severe nausea and vomiting that patients stop treatment." So at this year's Society for Neuroscience meeting in San Diego, Yacawych and other researchers held a session to describe their efforts to understand and solve the side-effect problem

Senescence-associated secretory phenotype

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It's important to note that these side effects are typically mild and often resolve on their own

These beta-arrestin-mediated signaling pathways may elicit distinct cellular responses, including mitogen-activated protein kinase (MAPK) activation, which hypothetically regulates cell growth, differentiation, and survival.

Incorporating process utility into quality adjusted life years: a systematic review of empirical studies