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Cellular pathways affected by ototoxic drugs In various cell types, the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) and the antioxidant response element (ARE) have been recognized as significant contributors in multiple cellular responses to oxidative stress (Kros and Steyger 2019
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S., Suffoletto, H
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The honest summary: this is a theoretical concern based on mechanism, not a documented adverse event
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